Seroprevalence of 17 pathogens from an integrated national serosurvey in Niue

Integrated serosurveillance (ISS), using multiplex bead assays to measure antibodies to multiple pathogens, can provide insights into population immunity and pathogen exposure. We estimated seroprevalence for neglected tropical diseases (NTDs), arboviruses, vaccine-preventable diseases, and enteric protozoa in Niue through a cross-sectional survey embedded within a World Health Organization (WHO) STEPwise survey from 24 February to 4 April 2025. Dried blood spots from participants aged ≥ 3 years were tested for 26 pathogen-specific antibodies.
Among 750 participants (median age 37 years…
We would like to thank all the staff at the Niue Department of Health and WHO for their support and without whom this study would not have been possible. We acknowledge our funders, the Global Institute for Disease Elimination (FADE2024/03), National... [1271 chars]
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